| ADR Ontology |
| ADR Term |
Cardiac failure |
| ADR ID |
BADD_A00773 |
| ADR Hierarchy |
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| Description |
A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION. | Heart failure involving the RIGHT VENTRICLE. | Heart failure caused by dysfunction of the MYOCARDIUM, leading to defective cardiac emptying (contraction) or filling (relaxation). | Heart failure accompanied by EDEMA, such as swelling of the legs and ankles and congestion in the lungs. | Heart failure involving the LEFT VENTRICLE. [MeSH] |
| MedDRA Code |
10007554 |
| MeSH ID |
D006333; D006333; D006333
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
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| Synonym |
| Cardiac failure | Cardiac failure (NOS) | Cardiac failure aggravated | Cardiac failure NOS | Cardiac function failed | Cardiac function failure | Cardiac insufficiency | Decompensation cardiac | Decompensation myocardial | Failure heart | Heart failure | Heart failure (NOS) | Heart failure, unspecified | Heart insufficiency | Heart insuffiency | Insufficiency cardiac | Myocardial contraction decreased | Myocardial decompensation | Decompensated heart failure | Recurrent cardiac decompensation | Heart failure with preserved ejection fraction | Heart Failure | Cardiac Failure | Heart Decompensation | Decompensation, Heart | Heart Failure, Right-Sided | Heart Failure, Right Sided | Right-Sided Heart Failure | Right Sided Heart Failure | Myocardial Failure | Congestive Heart Failure | Heart Failure, Congestive | Heart Failure, Left-Sided | Heart Failure, Left Sided | Left-Sided Heart Failure | Left Sided Heart Failure |
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| ADR Related Proteins |
| Protein Name |
UniProt AC |
TTD Target ID |
| Dipeptidyl peptidase 4 | P27487 | T31391 |
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| Drugs Leading to the ADR |
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